Laboratório de Imunogenética

VIANNA, P. ; CHIES, J. A. B. Distress conditions during pregnancy may lead to pre-eclampsia by increasing cortisol levels and altering lymphocyte sensitivity to glucocorticoids. Medical Hypotheses, 2011.

VIANNA, P. ; CHIES, J. A. B. . Gestação de Sucesso: o papel do sistema imune da mãe na aceitação ou rejeição do feto. Ciência Hoje , v. 45, p. 28-33, 2010.

VIANNA, P. ; Kniphoff, GS ; SANTOS, B. P. ; BAUER, M. E. ; DALMAZ, C. ; BANDINELLI, E. ; CHIES, J. A. B. . Association between Mannose-Binding Lectin gene polymorphisms and pre-eclampsia in Brazilian women. American Journal of Reproductive Immunology v. 63, p. 1-8, 2010

VIANNA, P. ; CHIES, J. A. B. . Maternal exposure to paternal antigens can modulate the foetus immune system and is associated with reduced atopy in the childhood. Bioscience Hypotheses , v. 1, p. 248-250, 2008.

VIANNA, P. ; DALMAZ, C. ; VEIT, T. D. ; TEDOLDI, C. ; Roisenberg, I ; CHIES, J. A. B. . Immunogenetics of pregnancy: Role of a 14-bp deletion in the maternal HLA-G gene in primiparous pre-eclamptic Brazilian women. Human Immunology v. 68, p. 668-674, 2007.

BADAUY CM, SANT´ANA FILHO M, GOMES SS, CHIES JAB. Ehlers-Danlos Syndrome (EDS) type IV. Review of the literature. Clinical Oral Investigations, v. 11, p. 183-187, 2007.

BRAGA LMGM, ROSA K, RODRIGUES B, MALFITANO C, CAMASSOLA M, CHAGASTELLES P, LACCHINI S, FIORINO P, SCHAAN B, IRIGOYEN MC, NARDI NB. Systemic delivery of adult stem cells improves cardiac function in spontaneously hypertensive rats. Clinical and Experimental Pharmacology & Physiology, 2007.

MENDEZ A, CHAGASTELLES P, PALMA E, NARDI NB, Schapoval EES. Thermal and alkaline stability of meropenem: degradation products and cytotoxicity. International Journal of Pharmaceutics, 2007 (aceito para publicação).

BOROWSKI LC, LOPES RP, GONZALEZ TP, DUMMER LA, CHIES JAB, SILVEIRA IG, KEISERMANN M, BAUER ME. Is steroid resistance related to multidrug resistance-I (MDR-I) in rheumatoid arthritis?. International Immunopharmacology, v. 7, p. 836-844, 2007.

LUISI SB, BARBACHAN JJD, CHIES JAB, SANT´ANNA FILHO M. Behavior of human dental pulp cells exposed to transforming growth factor-beta1 (TGFb1) and acidic fibroblast growth factor (aFGF) in culture. Journal of Endodontics, v. 33, p. 833-835, 2007.

VIANNA P, DALMÁZ CA, VEIT TD, TEDOLDI CA, ROISENBERG I, CHIES JAB. Immunogenetic of pregnancy: role of a 14-pb deletion in the HLA-G gene in primiparous pre-eclamptic Brazilian women. Human Immunology, v. 68, p. 668-674, 2007.

CHIES, JAB. On the haplotypic frequencies of the MBL2 gene among human populations (Letter to the Editor). Lupus (Basingstoke), v. 16, p. 838, 2007.

MOTA R, PINHEIRO-JUNIOR JW, GOMES MJP, PEIXOTO RM, MAIA FCL, BRITO MF, CHIES JAB, SNEL GGM, BERCHT BS, JUFFO GD. Paratuberculose em um rebanho bovino leiteiro no estado de Pernambuco, PE. Arquivos do Instituto Biológico, v. 74, p. 73-79, 2007.

CHIES JAB, ROSA SB, VOLTARELLI JC, PRANKE PH. The use of stem cells for the treatment of autoimmune diseases. Brazilian Journal of Medical and Biological Research, v. 40, p. online, 2007.

ISLAM MQ, MEIRELLES LDA S, NARDI NB, MAGNUSSON P, ISLAM K. Polyethylene glycol-mediated fusion between primary mouse mesenchymal stem cells and mouse fibroblasts generates hybrid cells with increased proliferation and altered differentiation. Stem Cells Dev. 2006 Dec;15(6):905-19.

CAÑEDO AD, SANTOS DG, CHIES JAB, KVITKO K, NARDI NB. Optimization of an electroporation protocol using the K562 cell line as a model: role of cell cycle phase and cytoplasmic DNAses. Cytotechnology (Dordrecht), v. 51, p. 141-148, 2006.

BEYER NARDI N, DA SILVA MEIRELLES L. Mesenchymal stem cells: isolation, in vitro expansion and characterization. Handb Exp Pharmacol. 2006;(174):249-82.

PRANKE P, HENDRIKX J, ALESPEITI G, Nardi N, RUBINSTEIN P, VISSER J. Comparative quan tification of umbilical cord blood CD34+ and CD34+ bright cells using the ProCount-BD and ISHAGE protocols. Braz J Med Biol Res, 39(7):901-6, 2006

SILVA FH, NARDI NB. From leading role to the backstage: Mesenchymal stem cells as packaging cell lines for in situ production of viral vectors. Med Hypotheses, 67(4):922-5, 2006.

SCHIENGOLD M, SCHWANTES L, RIBEIRO MF, LOTHHAIMER N, GONZALEZ TP, CHIES J AB, NARDI NB. Expression of mdr isoforms in mice during estrous cycle and under hormone stimulation. Genetics and Molecular Biology, v. PRELO, 2006.

MEIRELLES LS, CHAGASTELLES PC, NARDI NB. Mesenchymal stem cells reside in virtually all post-natal organs and tissues. Journal of Cell Science, 2006.

RINKE R, PERES A, MACHADO MB, CHIES JAB. Doença Inflamatória Intestinal - Uma abordagem imunogenética. Ciência em movimento, Porto Alegre RS, v. 15, n. 1, p. 19-25, 2006.

SILVA FH, DALBERTO TP, NARDI NB. Beyond retrovirus infection: HIV meets gene therapy. Genetics and Molecular Biology, Genetics and Molecular Biology, v. 29, n.2, p. 367-379, 2006.

ISLAM MQ, RINGE J, REICHMANN E, MIGOTTI R, SITTINGER M, MEIRELLES LS, NARDI NB, MAGNUSSON P, ISLAM K. Functional characterization of cell hybrids generated by induced fusion of primary porcine mesenchymal stem cells with an immortal murine cell line. Cell and Tissue Research. 2006 Oct;326(1):123-37.

KVITKO K, GASPAR PA, TORRES MR, HUTZ MH. CYP1A1, GSTM1, GSTT1, GSTP1 polymorphism in a Afro-brazilian population. Genetics and Molecular Biology, 2006.

REOLON GK, BRAGA LMGM, CAMASSOLA M, LUFT T, HENRIQUES JA, NARDI NB, ROESLER R. Long-term memory for aversive training is impaired in Idua-/- mice, a genetic model of mucopolysaccharidosis type I. Brain Research, v. 1076, n. 1, p. 225-230, 2006.

PEREIRA TV, SALZANO FM, MOSTOWSKA A, TRZECIAK WH, LINARES AR, CHIES JAB, SAAVEDRA C, NAGAMACHI C, HURTADO AM, HILL K, GUERRA DC, SILVAJUNIOR WA, BORTOLINI MC. Natural selection and molecular evolution in primate PAX9 gene, a major determinant of tooth development. Proceedings of the National Academy of Sciences of the United States of America, v. 103, n. 15, p. 5676-5681, 2006.

CHIES JAB, DRESCH C, CRUZ MS, SILVA G, BARROS E, BITTAR C, FRIEDRISCH J, SILLA, LMR. Immunosuppressive therapy for kidney transplant prevents vaso-occlusive crisis in a haemoglobin SC disease patient. Medical Hypotheses, v. 64, n. 1, p. 174-176, 2005.

BADAUY CM, BARBACHAN JJD, RADOS PV, SANT´ANNA FILHO M, CHIES JAB. A relationship between candida infection and immune cellular response in inflammatory hyperplasia. Oral Microbiology and Immunology, v. 20, p. 89-92, 2005.

HUNEMEIER T, NEVES AG, NORNBERG IF, HILL K, HURTADO AM, CARNESE FR, GOICOECHEA AS, HUTZ MH, SALZANO FM, CHIES, JAB. T cell and chemokine receptor variation in South Amerindian populations. American Journal of Human Biology, Estados Unidos, v. 17, n. 4, p. 515-518, 2005.

DELGADO-CANEDO A, CHIES JAB, NARDI NB. Induction of fetal haemoglobin expression in erythroid cells - a model based on iron availability signalling. Medical Hypotheses, v. 65, p. 932-936, 2005.

VIEIRA GF, CHIES JAB. Immunodominant Viral Peptides as Determinants of Cross-Reactivity in the Immune System - Can we develop wide spectrum viral vaccines ? . Medical Hypotheses, v. 65, p. 873-879, 2005.

VARGAS AE, MARRERO AR, SALZANO FM, BORTOLINI MC, CHIES JAB. CCR5delta32 frequencies in Brazilian populations. Brazilian Journal of Medical and Biological Research, v. 39(3):321-325, 2006.

VARGAS AE, SILVA MAL da, SILLA LMR, CHIES JAB. Polymorphisms of chemokine receptors and eNOS in Brazilian patients with sickle cell disease. Tissue Antigens, v. 66(6):683-690, 2005.

CAMASSOLA M, BRAGA LM, CANEDO AD, DALBERTO TP, MATTE U, BURIN M, GIUGLIANI R, NARDI NB. Nonviral in vivo gene transfer in the mucopolysaccharidosis I murine model. Journal of Inherited Metabolic Disease, v. 28(6):1035-1043, 2005.

PRANKE P, HENDRIKX J, DEBNATH G, ALESPEITI G, RUBINSTEIN , NARDI NB, VISSER J. Immunophenotype of hematopoietic stem cells from placental/umbilical cord blood after culture. Brazilian Journal of Medical and Biological Research, v. 38(12):1775-1789, 2005.

Nardi N. All the adult stem cells, where do they all come from? An external source for organ-specific stem cell pools. Medical Hypotheses, v. 64, n. 4, p. 811-817, 2005.

LUISI SB, BARBACHAN JJD, CHIES JAB, SANT´ANNA FILHO M. A cultura de células como ferramenta para estudos do comportamento pulpar. Revista da Faculdade de Odontologia de Porto Alegre, Porto Alegre RS, v. 45, n. 1, p. 3-8, 2004.

GASPAR PA, MOREIRA J, KVITKO K, TORRES MR, MOREIRA A, WEIMER TA. CYP1A1, CYP2E1, GSTM1, GSTT1, GSTP1, and TP53 polymorphisms: do they indicate susceptibility to chronic obstructive pulmonary disease and non-small-cell lung cancer?. Genetics and Molecular Biology, Brasil, v. 27, n. 2, p. 133-138, 2004.

KVITKO, K. ; NUNES, J. C. B. ; HUTZ, M. H. . (TTTA)n Polymorphism of CYP19 (aromatase gene) in Euro and Afro-Brazilians.. Genetics and Molecular Biology, Brasil, v. 27, n. 3, p. 335-336, 2004.

ROHR P, CAÑEDO AD, PASKULIN G, SCHULER I, NARDI NB, KVITKO K. Análise dos Polimorfismos GSTM1 e GSTT1 em Pacientes que Desenvolveram Leucemia. Revista Brasileira de Biociências, Porto Alegre, v. 2, n. 3, p. 135-166, 2004.

Cordero EAA, Silla LMR, Cañedo AD, Allebrandt WF, Fogliatto L, Nardi NB. Interaction between normal and CML hematopoietic progenitors and stroma influences abnormal hematopoietic development. Stem Cells and Development 13(3): 225-228. 2004.

Peres A, Hünemeier T, Cruz IM, Nardi NB, Chies JAB. T-cell receptor BV gene segment polymorphisms in healthy elderly individuals from the south of Brazil. European Journal of Immunogenetics 31(2):77-81. 2004.

Peres A, Bauer M, Cruz IB, Nardi NB, Chies JAB. Immunophenotyping and T cell proliferative capacity in a healthy aged population. Biogerontology 4(5): 295-302. 2003.

Santanna RT, Kalil RAK, Moreno P, Anflor LC, Corrêa D, Ludwig R, Barra M, Silva EFA, Nardi NB, Santanna JRM, Prates PR, Nesralla IA. Terapia Gênica com VEGF 165 para Angiogênes no Infarto Agudo do Miocárdio Experimental. Revista Brasileira de Cirurgia Cardiovascular 18(2):142-147. 2003.

Dresch C, Xavier R, Brenol JC, Nardi NB, Chies JAB. Analysis of two T cell receptor BV gene segment polymorphisms in Caucasoid Brazilian patients with rheumatoid arthritis. Immunology Letters, 90(2-3): 77-80. 2003.

Meirelles LS, Nardi NB. Murine marrow-derived mesenchymal stem cell: isolation, in vitro expansion, and characterization. British Journal of Haematology 123(4): 702-711. 2003.

Peres A, Nardi NB, Chies JAB. Imunossenescência - o envolvimento do compartimento de células T no envelhecimento. Biociências 11(2): 187-194. 2003.

Savaris R, Chies JA. Copper ions dynamically regulate beta3 integrin subunit expression in Ishikawa cells. Contraception 67(3): 247-249. 2003.

Chies JA, Hutz MH. High frequency of the CCR5delta32 variant among individuals from an admixed Brazilian population with sickle cell anemia. Braz J Med Biol Res 36(1): 71-75. 2003.

Alfonso ZZ, Souza MA, Castro S, Newmann J, Nardi NB. Monoclonal antibodies detecting differentiation antigens on human leukocytes. Immunology Letters 86(1): 53-55. 2003.

Dresch C, Nardi NB, Chies JAB. TCRBV3S1 and TCRBV18 gene segment polymorphisms in Brazilian Caucasoid and Black populations. European Journal of Immunogenetics 29(1): 11-15. 2002.

Kalil RA, Teixeira LA, Mastalir ET, Moreno P, Fricke CH, Nardi NB. Experimental model of gene transfection in healthy canine myocardium: perspectives of gene therapy for ischemic heart disease. Arquivos Brasileiros de Cardiologia 79(3): 228-232. 2002.

Nardi NB, Teixeira LAK, Silva EFA. Terapia gênica. Ciência & Saúde Coletiva 7 (1): 109-116. 2002.

Chies JA, Nardi NB. Sickle cell disease: a chronic inflammatory condition. Medical Hypotheses 57(1): 46-50. 2001.

Teixeira LAK, Fricke CH, Bonorino CB, Bogo MR, Nardi NB. An efficient gene transfer system for hematopoietic cell line using transient and stable vectors. Journal of Biotechnology 88 (2): 159-165. 2001.

Pranke P, Failace RR, Allebrandt WF, Steibel G, Schmidt F, Nardi N. Hematologic and immunophenotypic characterization of human umbilical cord blood. Acta Haematologica 105(2):71-76. 2001.

Dresch C, Marasca JA, Canabarro U, Xavier R, Brenol JC, Chies JAB. Linfócitos T, o rearranjo do receptor de células T (TCR) e a utilização de polimorfismos do TCR como marcadores em artrite reumatóide. Revista Brasileira de Reumatologia 41 (1): 21-26. 2001.

Rota CA, Lima JCP, Blaya C, Nardi NB. Consensus and variable region PCR analysis of Helicobacter pylori 3' region of cagA gene in isolates from individuals with or without peptic ulcer. Journal of Clinical Microbiology 39 (2): 606-612. 2001.

Schiengold M, Schwantes L, Schwartsmann G, Chies JAB, Nardi NB. Multidrug resistance gene expression during the murine ontogeny. Mechanisms of Ageing and Development 122 (3): 255-270. 2001.

Alfonso ZZ, Forneck ED, Allebrandt WF, Nardi NB. Establishment of an adherent cell layer from human umbilical cord blood. Genetics and Molecular Biology 23(3): 519-522. 2000.

Pasquali G, Nardi NB. Biossegurança: conceitos e legislação no Brasil e no mundo. Acta Biologica Leopoldensia 21: 15-33. 1999.

Meissner RV, Covas DT, Dias PMB, Job F, Leite M, Nardi NB. Analysis of mRNA transcripts in chronic myeloid leukaemia patients. Genetics and Molecular Biology 22: 475-479. 1999.

Gissler ACF, Nardi NB, Nonnig RB, Oliveira LG, Roehe PM. Classical swine fever virus in plasma and peripheral blood mononuclear cells of acutely infected swine. Journal of Veterinary Medicine 46(9):585-593. 1999.

Santos AL, Ripoll D, Nardi N, Bassani VL. Immunomodulatory effect of Achyrocline satureioides (LAM.) D.C. aqueous extracts. Phytotherapy Research 13: 65-6. 1999.

Nardi NB, Costa ZZA. The hematopoietic stroma. Brazilian Journal of Medical and Biological Research 32: 601-609. 1999.