HAIRY CELL LEUKEMIA (HCL) / TRICHOLEUKEMIA / LEUKEMIC RETICULOENDOTHELIOSIS (95 % of all HCLs): a form of (indolent) chronic leukemia Aetiology : Symptoms & signs : maculopapular rash (5%), ecchymoses and purpura (20%), bronchopulmonary infections (30%), massive splenomegaly (90%) => occupation syndrome (20-40%), mild hepatomegaly (50%), osteolysis (3%). Superficial lymphadenomegaly is rare, while splenic hilar lymphadenopathy is commonly seen at abdominal CT. Association with other autoimmune disorders such as vasculitis (expecially giant cell arteritis), glomerulonephritis, and AIHA. Jansen staging, 1982 : Laboratory examinations : Differential diagnosis : SMZL
Therapy : Codiagnosis : Prognosis : causes of death
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