HOMO SAPIENS DISEASES - COAGULOPATHIES

Table of contents :


  • congenital coagulopathies
  • hemorrhagic coagulopathies
  • thrombophilic coagulopathies
  • acquired coagulopathies
  • disseminated intravascular coagulation (DIC)
  • hypercoagulability
  • hypocoagulability


  • Laboratory examinations : severe deficiency of clotting factor II (2%; normal 50–200%), factor VII(3%; 50–200%), factor IX (6%; 50–200%), and factor X (1%; 50–200%), with preserved clotting factors V, VIII, XI, and XII. Protein Induced by Vitamin K Absence II (PIVKA-II)
    Therapy : Vitamin K prophylaxis for neonates, recommended since the 1960s, is supported by a Cochrane review. The UK national programme of vitamin K replacement at birth is associated with a decrease in the incidence of vitamin K deficiency bleeding, most importantly intracranial haemorrhageref1, ref2, with associated improvements in perinatal mortality, and short-term and long-term morbidities (1.2 to 1.8 per 100 000 births).

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