Research Lines



Psychosocial and Behavioral Factors as Determinants of Health Outcomes

Schizophrenic Psychoses: Etiology, Risk Factors and Biological and Psychosocial Interventions

Psychoanalytic Psychotherapies: Process and Effectiveness Studies

Quality of Life: Instruments and their application in mental disorders and other medical entities

Bipolar disorder

Attention Deficit / Hyperactivity Disorder

Mood and Anxiety Disorders: Clinical, psychobiology and therapeutic interventions


Description and Projects

Title: Psychosocial and Behavioral Factors as Determinants of Health Outcomes

Description: Includes the study of psychosocial factors, adaptive, cognitive and behavioral mechanisms related to different mental disorders and normal individuals.

Website: Center for Research on Alcohol and Drugs - CPAD

Responsible Teachers:
Flavio Pechansky

Adolescents HIV + and HIV -: psychiatric symptomatology and risk / protection factors
Evaluation of the efficacy of a psycho-educational technique for risk management skills in drug abusers and adolescents
Evaluation of the presence of criteria for substance abuse and dependence, adapted for extrinsic non-lactic sugars (Aenl) in obese and non-obese individuals
Psychiatric comorbidity and its association with psychoactive substances
Impact of substance use on Brazilian traffic
Methods of evaluating treatment outcomes in chemical dependence
Patterns of drug use and dependence in Brazilian rave culture
Prevalence of smoking and readiness stage for change in patients, employees and physicians at a University Hospital of Porto Alegre
Use, abuse and dependence of psychoactive substances in samples of the Brazilian population
Transcultural validation of the severity index (ASI) version 6 for Brazil


Title: Schizophrenic Psychoses: Etiology, Risk Factors and Biological and Psychosocial Interventions

Description: Includes the study of new neuropsychometric diagnostic methods, genetic, pharmacological and psychotherapeutic applied to schizophrenia and related psychoses.

Professor Responsible:
Paulo Silva Belmonte de Abreu

Clinical trials with innovative therapies independent of industry
Epidemiology of schizophrenia: study of population segment of Rio Grande do Sul using public database DATASUS
A case control study of serum adiponectin levels and obesity in schizophrenics and normal controls
Randomized controlled trial of the effect of the integrated psychosocial rehabilitation program (PIRP) on the quality of life of schizophrenic patients compared to usual intervention
Study of biological markers in a population at high risk for developing schizophrenia and bipolar disorder
Study of animal models of schizophrenia and stem cell intervention in reversing brain damage
Study of polymorphisms in genes of neurotransmitters, hormones, neurotrophins and regulators of gene expression in schizophrenics
Neuromodulation in mental disorders
Metabolic syndrome in schizophrenia: controlled study with healthy volunteers



Title: Psychoanalytic psychotherapies: process and effectiveness studies

Description: It covers studies that evaluate indication, aspects that influence the process and the outcome of psychotherapies of analytical orientation

Responsible Teachers:
Claudio Laks Eizirik
Lucia Helena Freitas Ceitlin

The relationship between process and outcome of brief dynamic psychotherapy
Factors of psychoanalytic supervision that influence the teaching and learning of transference and countertransference in the Psychoanalytic Society of Porto Alegre (SPPA)
Program of research development in psychoanalysis and psychoanalytic psychotherapy
Psychoanalysis and culture
A study of the association between the transference pattern and the therapeutic alliance of patients in analytically oriented psychotherapy


Title: Quality of Life: Instruments and their Application in Mental Disorders and Other Medical Entities

Description: This line covers psychometric aspects of measures in quality of life, as well as the use of quality of life as a factor in study and outcome in health.

Professor Responsible:
Marcelo Pio de Almeida Fleck

Evaluation of quality of life in patients with HIV through the World Health Organization (WHOQOL) quality of life assessment instrument - HIV / AIDS module
Depression and sleep deprivation
Effects of cognitive-behavioral therapy on the quality of life of patients with obsessive-compulsive disorder
Risk factors and follow-up of patients with gender identity disorder before and after sexual reassignment surgery
Influence of health status on religiosity, spirituality and personal beliefs, quality of life and the formation of depressive symptoms
Perception of quality of life by the spouse in patients with breast cancer
Quality of life and depression
Quality of life in the elderly
Quality of life in patients with physical and mental disabilities


Title: Bipolar Disorder

Description: Includes studies of pathophysiological mechanisms and diagnostic, clinical, pharmacological, etiological and psychosocial aspects of bipolar disorder.

Responsible Teachers:
Flávio Kapczinski
Márcia Kauer-Sant Anna
Clarissa Severino Gama
Keila Maria Ceresér

Inflammatory mediators in patients with Bipolar Disorder.
The interaction between Brain Derived Neurotrophic Factor (BDNF) and Cytokines (IL-1, IL-6, TNF-alpha) in Bipolar Humor Disorder.
Impact of Sexual Abuse on Brazilian Children: Cognitive Performance and Blood Dosage of the Brain Derived Neurotrophic Factor.] Clinical, Neuropsychological, and Biochemical Aspects of Bipolar Disorder: Comorbidity with Childhood Sexual Abuse and Traumatic Life Events.
Brain-Derived Neurotrophic Factor as a predictive means of response to treatment in bipolar depression and mania: a 16-week study.
Correlation between female sex hormones and BDNF levels in patients with Bipolar Disorder and Pre-Menstrual Disorder.
Allostatic burden, cognition and coping strategies in the course of Bipolar Disorder.
Association between fibrinogen and von Willebrand Factor in Bipolar Disorder and Schizophrenia.
The Role of C-Reactive Protein in Bipolar Mood Disorder and Schizophrenia.
Quality of sleep in patients with Bipolar Mood Disorder.
Clinical, neuropsychological and biochemical aspects of Bipolar Disorder in comorbidity with crack abuse.
Tianeptin as adjunctive treatment in bipolar depression: a randomized placebo-controlled trial.
Association of the Brain Derived Neurotrophic Factor VAL66MET polymorphism and episodic memory in Bipolar Disorder.
Insight, cognition and neurotrophins in the different polarities of Bipolar Disorder.
Atypical antipsychotics for continuation and maintenance treatment after an acute episode of mania.
Randomized, double-blind, placebo-controlled clinical trial to evaluate the effect of N-acetylcysteine as adjunctive therapy for the treatment of bipolar affective disorder.
Web site: Bipolar Children and Adolescents Program - ProCAB



Title: Attention Deficit / Hyperactivity Disorder

Description: It covers studies of the etiological, diagnostic, clinical, psychosocial and cognitive aspects, as well as of course and treatment of attention deficit / hyperactivity disorder.

Web site: Attention Deficit / Hyperactivity Disorder Program - ProDAH

Responsible Teachers
 Childhood and Adolescence:
-Luis Augusto Paim Rohde

- Claiton Henrique Dotto Bau
- Eugenio Horacio Grevet

Study of the effectiveness of psychopharmacological interventions in attention deficit hyperactivity disorder
Study of the effectiveness of psychosocial interventions in Attention Deficit / Hyperactivity Disorder
Neuropsychology study of Attention Deficit / Hyperactivity Disorder
Study of the molecular basis of Attention Deficit / Hyperactivity Disorder
Study of clinical characteristics and comorbidities of attention deficit / hyperactivity disorder
Prevalence, development and determinants of psychiatric disorders in pre-adolescence: a follow-up of birth to eleven years



Title: Mood and Anxiety Disorders: Clinical, Psychobiology and Therapeutic Interventions

Description: This sub-area aims to study the etiological, diagnostic, psychosocial and cognitive as well as course and treatment aspects of mood and anxiety disorders.

Responsible Teachers:
Aristides Volpato Cordioli
Elizeth Paz da Silva Heldt
Flávio Pereira Kapczinski
Gisele Gus Manfro
Marcelo Pio de Almeida Fleck

Follow-up of patients with obsessive compulsive disorder treated with cognitive behavioral therapy in a limited time group in the long term
Ambulatory research on anxiety disorders in childhood and adolescence: epidemiology, diagnosis, etiology and treatment of anxiety disorders in childhood and adolescence
Clinical and biochemical aspects of electroconvulsive therapy (ECT)
Molecular aspects of suicide
Molecular aspects of anxiety disorders
Evaluation of depression, defense mechanisms and quality of life in patients with fibromyalgia
Evaluation of response to cognitive-behavioral group therapy for panic disorder in the short and long term
Evaluation of personality disorder, psychodynamic aspects and defense mechanisms in patients with panic disorder before and after treatment
Effects of motivational interview on group tcc results in the treatment of OCD
Physical exercise, depression and quality of life
Environmental factors and vulnerability to axis I psychiatric disorders: a case-control study of early psychological trauma in borderline personality disorders (Borderline)
Neuropsychological profile in obsessive-compulsive disorder
Predictors of Cognitive-Behavioral Therapy in Groups in Patients with Obsessive-Compulsive Disorder
Prevalence of eating disorders in bipolar patients
Psychometric properties of CES-D in users of primary care services in Porto Alegre
Follow-up of depressed patients in the outpatient clinic
Translation, adaptation and validation of the Obsessive-Compulsive Inventory scales - OCI and the Obsessive-Compulsive Inventory-Revised - OCI-R
Anxiety disorder in childhood and adolescence

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