LaBDiM - Laboratório de Biofilmes e Diversidade Microbiana
UFRGS
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Publicações

2016

  1. Silva, L. N.; Zimmer, K. R.; Macedo, A. J.; Trentin, D. S. Plant Natural Products Targeting Bacterial Virulence Factors. Chemical Reviews, p. acs.chemrev.6b00184-9236, 2016.
  2. Vieira, P. B.; Silva, N. L.; GNS, S.; Silva, D. B.; Lopes, N. P.; Gnoatto, S.; Silva, M. V.; Macedo, A. J.; Bastida, J. ; TASCA, T.  Caatinga plants: Natural and semi-synthetic compounds potentially active against Trichomonas vaginalis. Bioorganic & Medicinal Chemistry Letters (Print), v. 26, p. 2229-2236, 2016.
  3. Duarte, M. ; Seixas, A. ; Carvalho, M. P. ; Tasca, T. ; Macedo, A. J. . Amaurocine: Anti-Trichomonas vaginalis protein produced by the basidiomycete Amauroderma camerarium. Experimental Parasitology, v. 161, p. 6-11, 2016.
  4. Aires, M. M. ; Treter, J. ; Braz, D. C. ; Krug, C. ; Macedo, Alexandre J. ; Junior, C. A. . Influence of oxinitrided surface in the production of a less susceptible titanium surface to skin-borne bacterial adhesion. Artificial Organs, 2016.
  5. Agostini, V. O. ; Macedo, A. J. ; Muxagata, E. . Evaluation of antibiotics as a methodological procedure to inhibit free-living and biofilm bacteria in marine zooplankton culture. Anais da Academia Brasileira de Ciências (Impresso), 2016.
  6. Frasson, A. P. ; Santos, O. ; Meireles, L. C. ; Macedo, A. J. ; Tasca, T. Five putative Nucleoside Triphosphate Diphosphohydrolases (NTPDases) genes are expressed in Trichomonas vaginalis. FEMS Microbiology Letters, 2016.

2015

  1. Silva, L. N. ; Trentin, D. S. ; Zimmer, K. R. ; Treter, J. ; Brandelli, C. L. C. ; Frasson, A. P. ; Tasca, T. ; da Silva, Alexandre Gomes ; Silva, M. V. ; Macedo, A. J. . Anti-infective effects of Brazilian Caatinga plants against pathogenic bacterial biofilm formation. Pharmaceutical Biology, v. 53, p. 464-468, 2015.
  2. Trentin, D. S. ; Silva, D. B. ; Frasson, A. P. ; Rzhepishevska, O. ; Silva, M. V. ; Pulcini, E. L. ; James, G. ; Soares, G. V. ; Tasca, T. ; Ramstedt, M. ; Giordani, R. B. ; Lopes, N. P. ; Macedo, A. J. . Natural Green Coating Inhibits Adhesion of Clinically Important Bacteria. Scientific Reports, v. 5, p. 8287, 2015.
  3. Vieira, P. B. ; Giordani, R. B. ; Macedo, A. J. ; Tasca, T. . Natural and synthetic compound anti-Trichomonas vaginalis: an update review. Parasitology Research (1987. Print), v. 114, p. 1249-1261, 2015.
  4. Vieira, P. B. ; Silva, N. L. ; Kist, L. W. ; Oliveira, G. M. T. ; Bogo, M. R. ; Decarli, G. A. ; Macedo, A. J. ; Tasca, T. . Iron from haemoglobin and haemin modulates nucleotide hydrolysis in Trichomonas vaginalis. Memórias do Instituto Oswaldo Cruz (Impresso), v. 110, p. 201-208, 2015.
  5. Becker, D. L. ; Santos, Odelta ; Frasson, A. P. ; Rigo, G. V. ; Macedo, A. J. ; TASCA, T. . High rates of double-stranded RNA viruses and Mycoplasma hominis in Trichomonas vaginalis clinical isolates in South Brazil. Infection, Genetics and Evolution (Print), v. 34, p. 181-187, 2015.
  6. Barros, M. P. ; Rigo, G. V. ; Frasson, A. P. ; Santos, O. ; Smirdele, L. ; Almeida, S. ; Macedo, A. J. ; Tasca, T. . Modulatory effect of iron chelators on adenosine deaminase activity and gene expression in Trichomonas vaginalis. Memórias do Instituto Oswaldo Cruz (Online), v. 110, p. 877-883, 2015.
  7. Santos, O. ; Rigo, G. V. ; Frasson, A. P. ; Macedo, A. J. ; Tasca, T. . Optimal reference genes for gene expression normalization in Trichomonas vaginalis. Plos One, v. 10, p. 1-17, 2015.
  8. Brandelli, C. L. C. ; Ribeiro, V. B. ; Zimmer, K. R. ; Barth, A. L. ; Tasca, T. ; Macedo, A. J. . Medicinal Plants Used by a Mbyá-Guarani Tribe Against Infections: Activity on KPC-Producing Isolates and Biofilm-Forming Bacteria. Natural Product Communications, v. 10, p. 1847-1852, 2015.

2014

  1. Bresciani, Fernanda R. ; Santi, Lucélia ; Macedo, Alexandre J. ; Abraham, Wolf-Rainer ; Vainstein, Marilene H. ; Beys-da-Silva, Walter O. . Production and activity of extracellular lipase from Luteibacter sp.. Annals of Microbiology, v. 64, p. 251-258, 2014.
  2. Scopel, M. ; Abraham, W.R ; Henriques, A. T. ; Macedo, A.J . Mevalonolactone: An Inhibitor of Staphylococcus Epidermidis Adherence and Biofilm Formation. Medicinal Chemistry (Hilversum), v. 10, p. 246-251, 2014.
  3. Zimmer, K. R. ; Blum-Silva, C. H. ; Souza, A. L. K. ; Schuch, M. W. ; Macedo, A.J ; Reginatto, F. H. ; Pereira, C. M. P. ; Lencina, C. L. . The Antibiofilm Effect of Blueberry Fruit Cultivars Against Staphylococcus epidermidis and Pseudomonas aeruginosa. Journal of Medicinal Food, v. 17, p. 324-331, 2014.
  4. Silva, L. A. D. ; Macedo, A.J ; Termignoni, C . Production of keratinase by Bacillus subtilis S14. Annals of Microbiology, v. 64, p. 1725-1733, 2014.
  5. Treter, J. ; Bonnato, F. ; Krug, C. ; Soares, G. V. ; Baumvol, I. J. R. ; Macedo, A.J . Washing-resistant surfactant coated surface is able to inhibit pathogenic bacteria adhesion. Applied Surface Science, v. 303, p. 147-154, 2014.
  6. Trentin, D.S ; Bonnato, F. ; Zimmer, K. R. ; Ribeiro, V. B. ; Antunes, A. L. S. ; Barth, A. L. ; Soares, G. V. ; Krug, C. ; Baumvol, I. J. R. ; Macedo, A.J . N2/H2 plasma surface modifications of polystyrene inhibit the adhesion of multidrug resistant bacteria. Surface & Coatings Technology, p. 84-91, 2014.
  7. Silva, L. A. D. ; Tirloni, L. ; Loss Morais, G. ; Margis, R. ; da Silva Vaz Jr, I. ; Macedo, A.J ; Termignoni, C . A recombinant subtilisin with keratinolytic and fibrin(ogen)olytic activity. Process Biochemistry (1991), v. 49, p. 948-954, 2014.
  8. Trentin, D. S. ; Zimmer, K. R. ; Silva, M. V. ; Giordani, R. B. ; Macedo, A. J. . Medicinal plants from brazilian caatinga: antibiofilm and antibacterial activities against Pseudomonas aeruginosa. Revista Caatinga (UFERSA. Impresso), v. 27, p. 264-271, 2014.
  9. Cabral, M. E. S. ; Vernieri, A. N. R. ; Macedo, A. J. ; Trentin, D.S ; Treter, J. ; Manzo, R. H. ; Valdez, J. C. . Formulation and quality control of semi-solid containing harmless bacteria by-products: chronic wounds pro-healing activity. Pharmaceutical Development and Technology (Print), v. ahead, p. 1-8, 2014.

2013

  1. Trentin D. S. ; Silva, D. B.; Amaral, M. W.; Zimmer, K. R.; Silva, M. V.; Lopes, N. P.; Giordani, R. B.; Macedo, A. J. Tannins Possessing Bacteriostatic Effect Impair Pseudomonas aeruginosa Adhesion and Biofilm Formation. PLoS One, 11;8(6):e66257, 2013.
  2. Scopel, M. ; Santos, O. ; Frasson, A. P. ; Abraham, W.R ; Henriques, A. T. ; Tasca, T. ; Macedo, A. J. . Anti-Trichomonas vaginalis activity of marine-associated fungi from the South Brazilian Coast. Experimental Parasitology, v. 133, p. 211-216, 2013.
  3. Zimmer, Karine Rigon ; Macedo, A. J. ; Giordani, R. B. ; Conceicao, J. M. ; Nicastro, G. ; Boechat, A. L. ; Baldini, R. L. ; Abraham, W. R. ; Termignoni, C . A steroidal molecule present in the egg wax of the tick Rhipicephalus (Boophilus) microplus inhibits bacterial biofilms. Environmental Microbiology (Print), 2013.
  4. Zimmer, Karine Rigon ; Macedo, A. J. ; Nicastro, G. G. ; Baldini, R. L. ; Termignoni, C . Egg-wax from cattle tick Rhipicephalus (Boophilus) microplus inhibits Pseudomonas aeruginosa biofilm. Ticks and Tick-borne Diseases, 2013.
  5. Scopel, M. ; Santos, O. ; Frasson, A. P. ; Abraham, W.R ; Henriques, A. T. ; Tasca, T. ; Macedo, A. J. . Anti-Trichomonas vaginalis activity of marine-associated fungi from the South Brazilian Coast. Experimental Parasitology, v. 133, p. 211-216, 2013.
  6. Scopel, M. ; Abraham, W.R ; Henriques, A. T. ; Macedo, A. J. . Dipeptide cis-cyclo(Leucyl-Tyrosyl) produced by sponge associated Penicillium sp. F37 inhibits biofilm formation of the pathogenic Staphylococcus epidermidis. Bioorganic & Medicinal Chemistry Letters (Print), v. 23, p. 624-626, 2013.
  7. Zimmer, K. R. ; Seixas, A. ; Conceicao, J. M. ; Zvoboda, D. A. ; Barros, M. P. ; Tasca, Tiana ; Macedo, A. J. ; Termignoni, C . Cattle tick-associated bacteria exert anti-biofilm and anti-Tritrichomonas foetus activities. Veterinary Microbiology (Amsterdam. Print), v. 164, p. 171-176, 2013.
  8. Brandelli, Clara Lia Costa ; Vieira, P. B. ; Macedo, A. J. ; Tasca, T. . Remarkable Anti-Trichomonas vaginalis Activity of Plants Traditionally Used by the Mbyá-Guarani Indigenous Group in Brazil. Journal of Biomedicine and Biotechnology (Print), v. 2013, p. 1-7, 2013.
  9. Silva, L. C. N ; Miranda, R. C. M. ; Gomes, E. B. ; Macedo, A.J ; Araujo, J. M. ; Figueiredo, R. C. B. Q. ; Silva, M. V. ; Correia, M. T. S. . Evaluation of combinatory effects of Anadenanthera colubrina, Libidibia ferrea and Pityrocarpa moniliformis fruits extracts and erythromycin against Staphylococcus aureus. Journal of Medicinal Plant Research, v. 7, p. 2358-2364, 2013.
  10. Silva, J.F.V ; Silva, L. C. N ; Arruda, I. R. S. ; Silva, A. G. ; Macedo, A. J. ; Correia, M. T. S. ; Silva, M. V. ; Silva, M. V. . Antimicrobial activity of Pityrocarpa monilifomis leaves and its capacity to enhance the activity of four antibiotics against Staphylococcus aureus strains. Journal of Medicinal Plant Research, v. 7(28), p. 2067-2072, 2013.

2012

  1. Pessi, I. S. ; Elias, S. O. ; Simões, F. L. ; Simões, J. C. ; Macedo, A. J. . Functional diversity of microbial communities in soils at the vicinity of Wanda glacier, Antarctic Peninsula. MICROBES ENVIRON, v. 27, p. 200-203, 2012.
  2. Melo-Silveira, Raniere Fagundes ; Fidelis, Gabriel Pereira ; Costa, Mariana Santana Santos Pereira ; Telles, Cinthia Beatrice Silva ; Dantas-Santos, Nednaldo ; Elias, Susana de Oliveira ; Ribeiro, Vanessa Bley ; Barth, Afonso Luis ; Macedo, Alexandre José ; Leite, Edda Lisboa ; Rocha, Hugo Alexandre Oliveira . In Vitro Antioxidant, Anticoagulant and Antimicrobial Activity and in Inhibition of Cancer Cell Proliferation by Xylan Extracted from Corn Cobs. International Journal of Molecular Sciences (Online), v. 13, p. 409-426, 2012.
  3. Saito, Samuel Takashi ; Trentin, Danielle da Silva ; Macedo, Alexandre José ; Pungartnik, Cristina ; Gosmann, Grace ; Silveira, Jaqueline de Deos ; Guecheva, Temenouga Nikolova ; Henriques, João Antonio Pêgas ; Brendel, Martin . Bioguided Fractionation Shows Cassia alata Extract to Inhibit Staphylococcus epidermidis and Pseudomonas aeruginosa Growth and Biofilm Formation. Evidence-Based Complementary and Alternative Medicine (Print), v. 2012, p. 1-13, 2012.
  4. Brandelli, Clara Lia Costa ; Carli, Geraldo Attilio De ; Macedo, Alexandre José ; Tasca, Tiana . Intestinal parasitism and socio-environmental factors among Mbyá-Guarani indians, Porto Alegre, Rio Grande do Sul, Brazil. Revista do Instituto de Medicina Tropical de São Paulo (Impresso), v. 54, p. 119-122, 2012.
  5. Frasson, A. P. ; Santos, O. ; Duarte, M. ; Trentin, D. S. ; Giordani, R. B. ; Silva, A. G. ; Silva, M. V. ; Tasca, T. ; Macedo, A. J. . First report of anti-Trichomonas vaginalis activity of the medicinal plant Polygala decumbens from the Brazilian semi-arid region, Caatinga. Parasitology Research (1987. Print), v. 110, p. 2581-2587, 2012.
  6. De Oliveira, Ygor Lucena Cabral ; Nascimento Da Silva, Luis Cláudio ; da Silva, Alexandre Gomes ; Macedo, Alexandre José ; ARAÚJO, JANETE MAGALI DE ; Correia, Maria Tereza dos Santos ; Silva, Márcia Vanusa da . Antimicrobial Activity and Phytochemical Screening of Buchenavia tetraphylla (Aubl.) R. A. Howard (Combretaceae: Combretoideae). The Scientific World Journal, v. 2012, p. 1-6, 2012.

2011

  1. Antunes, A. L. S. ; Bonfanti, J. W. ; Perez, Leandro Reus Rodrigues ; Pinto, Camille Cattani Ferreira ; Freitas, Ana Lúcia Peixoto de ; Barth, Afonso Luis ; Macedo, Alexandre José . High vancomycin resistance among biofilms produced by Staphylococcus species isolated from central venous catheters. Memórias do Instituto Oswaldo Cruz (Impresso), v. 106, p. 51-55, 2011.
  2. Trentin, D.S ; Gorziza, D. F ; Abraham, W.R ; Antunes, A.L.S ; Lerner, C ; Mothes, B ; Termignoni, C ; Macedo, A.J . Antibiofilm activity of Cobetia marina filtrate upon Staphylococcus epidermidis catheter-related isolates. Brazilian Journal of Microbiology (Impresso), v. 42, p. 1329-1333, 2011.
  3. Silva, L. C. N. ; Silva Junior, C. A. ; Souza, R. M. ; Macedo, A. J. ; Silva, M. V. ; Correia, M. T. S. . Comparative analysis of the antioxidant and DNA protection capacities of Anadenhantera colubrina, Libidibia ferrea and Pityrocarpa moniliformis fruits. Food and Chemical Toxicology, v. 49, p. 2222-2228, 2011.
  4. Trentin, Danielle da Silva ; Giordani, Raquel Brandt ; Zimmer, Karine Rigon ; da Silva, Alexandre Gomes ; da Silva, Márcia Vanusa ; Correia, Maria Tereza dos Santos ; Baumvol, Israel Jacob Rabin ; Macedo, Alexandre José . Potential of medicinal plants from the Brazilian semi-arid region (Caatinga) against Staphylococcus epidermidis planktonic and biofilm lifestyles. Journal of Ethnopharmacology, v. 137, p. 327-335, 2011.

2010

  1. Antunes, A. L. S. ; Trentin, D. S. ; Pinto, C. C. F. ; Perez, L. R. R. ; Macedo, Alexandre José ; Barth, A. L. . Application of a feasible method for determination of biofilm antimicrobial susceptibility in staphylococci. APMIS. Acta Pathologica, Microbiologica et Immunologica Scandinavica, v. 118, p. 873-877, 2010.

2009

  1. Macedo, Alexandre J. ; Macedo, A. J. . Can Infectious Biofilm be Controlled by Blocking Bacterial Communication?. Medicinal Chemistry (Hilversum), v. 5, p. 517-528, 2009.
  2. Duarte, Mariana ; Giordani, Raquel Brandt ; Carli, Geraldo Attilio De ; Zuanazzi, José Angelo ; Macedo, Alexandre José . Cytotoxicity of solubilization vehicles for Trichomonas gallinae and Tritrichomonas foetus measured by the resazurin microtiter assay. Veterinary Parasitology (Print), v. 166, p. 167-170, 2009.
  3. Duarte, M. ;  Giordani, R. B. ; De Carli, G. A. ; Zuanazzi, J. A. S. ; Macedo, A. J. ; Tasca, T. . A quantitative resazurin assay to determinate the viability of Trichomonas vaginalis and the cytotoxicity of organic solvents and surfactant agents. Experimental Parasitology, v. 123, p. 195, 2009.

2008

  1. Macedo, A. J. ; Silva, W. O. B. ; Termignoni, C. . Properties of a non collagen-degrading Bacillus subtilis keratinase. Canadian Journal of Microbiology, v. 54, p. 180-188, 2008.
  2. Abraham, W. R. ; Macedo, A. J. ; Lunsdorf, H. ; Fischer, R. ; Pawelczyk, S. ; Smit, J. ; Vancanneyt, M. . Phylogeny by a polyphasic approach of the order Caulobacterales, proposal of Caulobacter mirabilis sp. nov., Phenylobacterium haematophilum sp. nov. and Phenylobacterium conjunctum sp. nov., and emendation of the genus Phenylobacterium. International Journal of Systematic and Evolutionary Microbiology, v. 58, p. 1939-1949, 2008.



Laboratório de Biofilmes & Diversidade Microbiana
Universidade Federal do Rio Grande do Sul
Centro de Biotecnologia
Av. Bento Gonçalves 9500 - Setor IV - Prédio 43431 - Lab. 217
Bairro Agronomia - Porto Alegre/RS - Brasil
CEP 915901-970
Telefone: (51) 3308 6082
Atualizado em: março/2018
Dr. Alexandre José Macedo
Universidade Federal do Rio Grande do Sul
Faculdade de Farmácia
Av. Ipiranga 2752 - Sala 709
Bairro Santana - Porto Alegre/RS - Brasil
CEP 90610-000
Telefone: (51) 3308 5354
E-mail
UFRGS