As esiCancer is a software from Unsigned Developer, users with macOS High Sierra or less need perform the followed steps for installation.

1. Download esiCancer from website and open the software setup file.
   
   


2. A pop-up window will open with an error. Click "OK".
   
   


3. Open the Apple Menu. Select the "System Preferences" option.
   
   


4. Click on "Security & Privacy".
   
   


5. Click the lock icon to alow changes on your mac.
   
   


6. Enter your Username and Password, the click Unlock. This will allow changes on General configurations.
   
   


7. Click the "Open Anyway" button next to esiCancer name.
   
   


8. A pop-up window will open, next press the "Open" button.
   
   


9. Now you can open esiCancer normally and start your simulation.