[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Ana Maria” module_id=”A” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/default-avatar.jpg” title_text=”default-avatar” align=”center” _builder_version=”4.4.8″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n
\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 1B | Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n STUDY OF PURINERGIC SIGNALING IN TUMORS AND PATHOLOGIES IN THE CENTRAL NERVOUS SYSTEM AND ITS RELATIONSHIP WITH IMUNE SYSTEM<\/strong><\/p>\n In this line of research we have addressed purinergic signaling in four main aspects: a) evaluation of the enzymatic activity and expression of ecto-nucleotidases (NTPDases \/ CD39, ecto-5\u2032-nucleotidase \/ CD73) and purinergic receptor expression and functionality of tumors in the nervous system (gliomas and meduloblatomas) and in the bladder; B) the study of the role of the enzymes NTPDase1 \/ CD39 and ecto-5\u2032-NT \/ CD73 in cells of the immune system; C) The enzyme ecto-5\u2032-nucleotidase as potential new pharmacological target in cancer. In this sense we have made a molecular modeling approach in the search for new molecules inhibiting this enzyme and, d) the role of purinergic receptors, especially P2X7, in central nervous system disorders involving neuroinflammation and neuroprotection.<\/p>\n Concentration Areas: <\/strong> Cellular Biology<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Andr\u00e9 Quincozes” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/andre_quincozes_santos.jpg” title_text=”andre_quincozes_santos” align=”center” _builder_version=”4.9.0″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 1D Research Productivity Scholarship | Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n NEUROTOXICITY AND GLIOPROTECTION<\/strong><\/p>\n Astrocytes are extremely versatile cells, fundamental for the maintenance of homeostasis in the central nervous system. The use of astrocyte cultures from adult and aged animals is an important new tool in the understanding of astrocytic functionality related to aging and, consequently, age-related diseases. In this line, we investigate the mechanisms of glioprotection against neurotoxic conditions both in vivo and in vitro, as well as the glioprotective potential of antioxidants.<\/p>\n Concentration Areas: <\/strong>Neurochemistry, Neuropharmacology and Behaviour<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Angela Terezinha de Souza Wyse” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/angela_wise.jpg” title_text=”angela_wise” align=”center” _builder_version=”4.9.0″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 1A | Master’s Advisor | Doctoral Advisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n NEUROBIOLOGY OF BRAIN DISEASES AND THEIR NEUROPROTECTION<\/strong><\/p>\n Investigation of neurochemical, morfological and behavioral mechanisms in experimental model mimicking physiological and\/or pathological conditions, focusing on tissue accumulation of neurotoxic compounds accumulated in innate errors of the metabolism, mainly homocysteine, an amino acid considered a risk factor for neurometabolic, neurodegenerative, psychiatric, cancer and cerebral and cardiac ischemia, with emphasis on neuroprotection. The role of Na +, K + -ATPase, bioenergetics, cholinergic and glutamatergic homeostasis, oxidative and inflammatory status in the pathophysiology of these diseases, as well as the neurobiology of menopause are also studied. Biochemical and behavioral mechanisms of methylphenidate are also investigated at central and peripheral levels <\/p>\n Concentration Areas: <\/strong> Neurochemestry, Neuropharmacology, and Behaviour: Innate Errors of the Metabolism<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Carla Dalmaz” module_id=”C” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/carla_dalmaz.jpeg” title_text=”carla_dalmaz” align=”center” _builder_version=”4.9.2″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 1B | Master’s Advisor | Doctoral Advisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n STRESS NEUROBIOLOGY<\/strong><\/p>\n Studies the impact of stress at different development stages on behavior, using animal models. Stress at sensitive periods during postnatal development leads to nervous system programming with distinct behavioral outcomes, including memory, attention, and anxiety. These changes are object of study of the group. Neurochemical parameters related to such effects, such as oxidative stress and neurotransmitter systems, are also studied. The effects on eating behavior and metabolism and the interaction of stress during development with the consumption of palatable diets are also the focus of the laboratory study.<\/p>\n Concentration Areas: <\/strong> Neurochemistry, Neuropharmacology and Behaviour<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Carlos Alberto Saraiva Gon\u00e7alves” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/carlos_alberto_saraiva.jpg” title_text=”carlos_alberto_saraiva” align=”center” _builder_version=”4.9.0″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 1A | Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n PROTEIN S100B IN NEUROGLIAL PLASTICITY<\/strong><\/p>\n Astrocytes, the most abundant cells of the CNS, act on metabolic regulation, antioxidant defense, synaptic modulation and inflammatory response. S100B, a calcium binding protein, is secreted by astrocytes and exerts trophic (or toxic) activity on neighboring cells via RAGE and TLR receptors. Changes in the expression and activity of this protein have been associated with several neurodegenerative diseases (e.g., Alzheimer\u2019s disease and diabetes mellitus) and other neuropsychiatric disorders. In this line we investigated S100B and other glial proteins (GFAP, glutamine synthetase, calcineurin and ApoE) in several clinical situations, dementia models and neuroprotection strategies.<\/p>\n Concentration Areas:<\/strong> Nutrition, Metabolism, Oxidative Stress<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Carlos Alexandre Netto” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/carlos_alexandre_netto.jpg” title_text=”carlos_alexandre_netto” align=”center” _builder_version=”4.9.2″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 1A | Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n EXPERIMENTAL NEUROPROTECTION IN MODELS OF CEREBRAL ISCHEMIA AND RAQUIMEDULAR INJURY<\/strong><\/p>\n Studies about mechanisms of cell death and neuroprotection in models of chronic neurological pathologies of great incidence and morbidity, such as cerebral ischemia in adults and in newborns or as spinal cord injuries, as well as in the process of senescence. We especially studied neuroplasticity, glial function and inflammatory modulation, with the final outcome of functional, cognitive or motor recovery following pharmacological treatments with innovative and non-pharmacological molecules such as physical exercise, environmental stimulation and skill training.<\/p>\n Concentration Areas: <\/strong> Neurochemistry, Neuropharmacology, and Behaviour<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Carmem Juracy Silveira Gottfried” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/default-avatar.jpg” align=”center” _builder_version=”4.9.3″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 1C | Master’s Advisor | Doctoral Advisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n DISORDERS OF THE AUTISM SPECTRE<\/strong><\/p>\n Autism Spectrum Disorder (ASD) is a multifactorial neural development disorder with varying degrees of presentation, characterized by (1) changes in social communication and social interaction in multiple contexts and (2) repetitive behaviors, restricted activities and interests. One of the strengths of this line is the interchange of knowledge between clinical and basic research, together with the opening of space for discussion and training of other health professionals, particularly in clinical practice, in the search for innovative therapeutic strategies.<\/p>\n Concentration Areas:<\/strong> Neurochemistry, Neuropharmacology, and Behaviour<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Carmen Regla Vargas” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/carmen_regla_vargas_page-0001.jpg” title_text=”carmen_regla_vargas_page-0001″ align=”center” _builder_version=”4.9.0″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 1C | Master’s Advisor | Doctoral Advisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n OXIDATION STRESSES IN METABOLIC DISEASES<\/strong><\/p>\n This research line aims to study the in vitro and in vivo effects of metabolites accumulated in metabolic diseases inherited under oxidative stress and inflammatory processes. For this, different parameters of oxidative stress in human and animal tissues will be investigated. Patients will be studied at diagnosis and throughout the treatment in order to better understand the pathophysiology of these diseases, as well as to evaluate the effect of the treatment of these pathologies on the parameters of oxidative damage and inflammation.<\/p>\n Concentration Areas:<\/strong> Innate Errors of the Metabolism<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Clarissa Severino Gama” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/clarissa-_gama.jpg” title_text=”clarissa _gama” align=”center” _builder_version=”4.9.0″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 1D Research Productivity Scholarship | Master’s Advisor | Doctoral Advisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n Neuroprogression in Severe Psychiatric Disorders<\/strong><\/p>\n Investigate the biological underpinnings of the decline in cognition, physical health and functioning that takes place among patients with bipolar disorder and schizophrenia. The group has been studying biomarkers (systemic and brain imaging) and cognitive performance in order to understand the mechanisms to avoid disease progression and daily functioning decline; contributing to the notion that bipolar disorder and schizophrenia are systemic and progressive illnesses.<\/p>\n Concentration Areas:<\/strong> Neuroprogression, Behaviour, Psychopharmacology<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Clovis Milton Duval Wannmacher” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/default-avatar.jpg” align=”center” _builder_version=”4.4.8″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 1C | Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n EXPERIMENTAL STUDIES IN INTEGRATED ERRORS OF AMINO ACID METABOLISM<\/strong><\/p>\n Study of behavioral and metabolic changes in chemical models of innate errors of amino acid metabolism in rats: oxidative stress, phosphoryl transfer and protection by creatine and pyruvate.<\/p>\n Concentration Areas:<\/strong> Innate Errors of the Metabolism<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Cristiane Matt\u00e9” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/cristiane_matte.jpg” title_text=”cristiane_matte” align=”center” _builder_version=”4.9.0″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Master’s Advisor | Doctoral Advisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n METABOLIC PROGRAMMING<\/strong><\/p>\n Gestation is a critical period for the development and programming of the organism in formation, and can be altered by several factors, such as nutrition, hormones, stressors and physical exercise. Our objective is to evaluate the effect of these factors during maternal gestation in rats on behavioral and biochemical parameters in the central nervous system of pups. Study of behavioral and metabolic changes in chemical models of innate errors of amino acid metabolism in rats: oxidative stress, phosphoryl transfer and Protection by creatine and pyruvate.<\/p>\n Concentration Areas:<\/strong> Nutrition, Metabolism, Oxidative Stress<\/p>\n INNATE ERRORS OF THE METABOLISM<\/strong><\/p>\n We seek to clarify the mechanisms of neuro and hepatotoxicity of compounds accumulated in Inborn Errors of Metabolism, as well as to identify therapeutic strategies aimed at preventing or reversing the damages caused by these compounds.<\/p>\n Concentration Areas:<\/strong> Innate Errors of the Metabolism<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Daniel Pens Gelain” module_id=”D” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/default-avatar.jpg” align=”center” _builder_version=”4.4.8″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 2 | Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n REDOX-ACTIVE SIGNALING IN NERVOUS AND IMUNE SYSTEMS<\/strong><\/p>\n To elucidate cell signaling mechanisms by which reactive species (free radicals) control processes of regulation in the cell cycle, neuronal function and modulation of the inflammatory response, in order to establish new therapeutic targets for neurodegenerative diseases and disorders related to pro-inflammatory conditions.<\/p>\n Concentration Area: <\/strong> Cellular Biology<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Diogo L\u00f6sch de Oliveira” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/diogo_losch.jpg” title_text=”diogo_losch” align=”center” _builder_version=”4.9.2″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n MOLECULAR MECHANISMS IN NEURODEGENERATIVE DISEASES<\/strong><\/p>\n Our research line studies the cellular and molecular mechanisms involved in neurodegenerative diseases, emphasizing the role of the glutamatergic system in the excessive stimulation of ion channels and signaling pathways in nerve cells. In addition, the laboratory seeks to develop and evaluate new pharmacological neuroprotection strategies.<\/p>\n Concentration Areas:<\/strong> Neurochemestry, Neuropharmacology, and Behaviour\/p>[\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Diogo Onofre Gomes de Souza” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/diogo_onofre_souza.jpg” title_text=”diogo_onofre_souza” align=”center” _builder_version=”4.9.0″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 1A | Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n CEREBRAL INJURY\/NEUROPROTECTION: INTERACTION BETWEEN EXTRACELLULAR GUANOSIN AND THE GLUTAMATERGIC SYSTEM: POSSIBLE GUANOSINE ROLE AS NEUROPROTECTOR<\/strong><\/p>\n To identify the cerebral mechanisms involved in the neuroprotective effects of guanosine against glutamatergic excitocity. To identify possible therapeutic relevance of the neuroprotective effects of guanosine.<\/p>\n Concentration Areas:<\/strong> Neurochemestry, Neuropharmacology, and Behaviour<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Eduardo Rigon Zimmer” module_id=”E” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/eduardo_zimmer.jpeg” title_text=”eduardo_zimmer” align=”center” _builder_version=”4.9.0″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship Level 2 | Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n NEUROIMAGING IN BRAIN DISEASES<\/strong><\/p>\n My research group uses refined neuroimaging techniques via Positron Emission Tomography (PET) to understand pathophysiological events in Alzheimer’s Disease. Our approach has a high translational character, as our studies combine image data in experimental models with data from clinical images. Currently, we have 5 well-defined lines of research: 1) Neuron-glia communication in Alzheimer’s Disease; 2) Metabolic networks in Alzheimer’s Disease; 3) Recognition of patterns in Alzheimer’s disease based on algorithms; 4) Development of a platform for the identification of beta-amyloid anti-oligomer compounds; and 5) Modifiable risk factors in Alzheimer’s disease.\n<\/p>\n Concentration Area: [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”F\u00e1bio Klamt” module_id=”F” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/fabio_klant.jpg” title_text=”fabio_klant” align=”center” _builder_version=”4.9.0″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 1D Research Productivity Scholarship | Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n USE OF THE DIFFERENTIATED HUMAN NEUROBLASTOMAN LINEAGE SH-SY5Y AS AN ALTERNATIVE MODEL IN NEUROSCIENCES<\/strong><\/p>\n The nervous system is pre-disposed to oxidative stress, and it is well established that many neurodegenerative diseases present this pathophysiological mechanism in common. But the molecular mechanisms of degeneration are not elucidated. For this reason, cellular models are important and use neurotoxins to mimic neurodegeneration. Our laboratory characterized an in vitro dopaminergic cell model through cellular differentiation of SH-SY5Y neuroblastoma induced by retinoic acid for 7 days. These cells present morphological and biochemical characteristics (presence of neurites and increased immunocontent of markers of neuronal differentiation) of a dopaminergic neuron. Since the production of reactive species is important in neurodegeneration, the search for and description of new antioxidant molecules with neuroprotective potential are therapeutic targets.<\/p>\n STUDY OF BIOMARKERS IN LUNG CARCINOMA<\/strong><\/p>\n Worldwide, lung carcinoma has the highest mortality rate among malignant neoplasms. Despite advances in lung cancer studies, improvement in the diagnosis, prognosis and treatment of patients are still objectives to be achieved. The identification of biomarkers constitutes a possibility of staging aid and an important step in individualized therapy and, ultimately, in increasing patient survival. This line of research seeks to characterize the prognostic and predictive potential of several biomarkers for lung carcinomas through cell lineage studies, database meta-analysis and in patient biopsies.o.<\/p>\n Concentration Areas:<\/strong> Cellular Biology<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Fabr\u00edcio Figueir\u00f3” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/fabricio_figueiro.jpg” title_text=”fabricio_figueiro” align=”center” _builder_version=”4.9.0″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Master’s Advisor | Doctoral supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n MODULATION OF THE IMMUNE SYSTEM IN CANCER<\/strong><\/p>\n In this line of research, we seek to understand and modulate the immune system in solid tumors (gliomas, medulloblastomas and bladder cancer) in three main aspects: Concentration Area: [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”F\u00e1tima Theresinha Costa Rodrigues Guma” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/fatima_guma.jpg” title_text=”fatima_guma” align=”center” _builder_version=”4.9.0″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 2 | Master’s Advisor | Doctoral Advisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n STUDY OF THE MECHANISMS OF DIFFERENTIATION, PROLIFERATION AND CELL VIABILITY<\/strong><\/p>\n The study of mechanisms that induce or impede differentiation and proliferation or alter cell viability are important both for tumor growth control and for enhancing the use of stem cells in tissue regeneration. In this sense it is relevant to investigate compounds with the potential to become adjuvants in conventional therapies. The recognition of pluripotency of hepatic stellate cells (HSC) has increased the interest about their part in liver regeneration, therefore studies to clarify the mechanisms involved in the phenotypic modulation of these cells are of great interest for the development of new forms of disease control. In this sense, we have developed studies aiming to find the effects of overexpression and gene silencing, such as Caveolina1 (Cav-1), Sirt-1 and PPARg in a HSC model. Using as a model lineages of transformed cells, hepatic stellate cells and derived adipose stem cells, we propose to analyze the effects of compounds such as: doxazosin, resveratrol, ogama-orizanol and Thuyaoccidentalis extract on the viability, proliferation and \/ Or the differentiation of these cells.<\/p>\n Concentration Areas:<\/strong> Cellular Biology<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Guilhian Leipnitz” module_id=”G” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/guilhian.jpg” title_text=”guilhian” align=”center” _builder_version=”4.9.0″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 2 | Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n RESEARCH OF PHYSIOPATHOLOGICAL MECHANISMS INVOLVED ON TISSUE DAMAGE IN ORGANIC ACIDEMIAS AND AMINOACIDOPATHIES<\/strong><\/p>\n This research aims to evaluate possible pathophysiological mechanisms involved in tissue damage, mainly neurological, observed in aminoacidopathies and organic acidemias. We used experimental models in vivo and in vitro to evaluate the effects of metabolites that accumulate in these diseases on energy and redox homeostasis, mitochondrial function and cell signaling pathways. It also studies the effects of antioxidant compounds, energetic substrates and Glutamatergic antagonists in animal models in vitro and in vivo of hereditary metabolic diseases.<\/p>\n Concentration Areas:<\/strong> Innate Errors in the Metabolism<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Jade de Oliveira” module_id=”J” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/jade_oliveira.jpg” title_text=”jade_oliveira” align=”center” _builder_version=”4.9.0″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curr\u00edculo” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Master’s Advisor \/ Doctoral Advisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ _module_preset=”default” open=”off”]<\/p>\n METABOLIC DISEASES AND THE DEVELOPMENT OF NEUROPATHOLOGIES. STUDY OF POSSIBLE THERAPEUTIC STRATEGIES. A worldwide phenomenon is the significant increase in life expectancy, and consequently in the number of individuals affected by neurodegenerative diseases, such as those that represent the main causes of dementia, Alzheimer’s and Parkinson’s diseases. In recent years, evidence has shown the relationship between metabolic diseases, such as hypercholesterolemia and obesity, and the development of these neuropathologies. Thus, the study of therapeutic interventions for metabolic diseases is of particular importance, in view of the high prevalence of these pathologies in the world population, as well as the relevance of their consequences. In this sense, our goal is to evaluate neuroprotection strategies to prevent or mitigate the effects of metabolic diseases on brain structures.\n<\/p>\n Concentration Areas:<\/strong> Neurochemistry, Neuropharmacology and Behavior<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Jos\u00e9 Cl\u00e1udio Fonseca Moreira” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/jose_claudio_fonseca_moreira.jpg” title_text=”jose_claudio_fonseca_moreira” align=”center” _builder_version=”4.9.2″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 1A | Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n REACTIVE SPECIES AND THEIR EFFECTS ON BIOLOGICAL SYSTEMS<\/strong><\/p>\n This research aims to evaluate of the role of reactive species as markes in the most important biochemical processes of biological systems in both normal and pathological physiological processes, as well as their role in cell differentiation and growth. Search and evaluation of natural or synthetic compounds with active redox properties.<\/p>\n Concentration Areas:<\/strong> Nutrition, Metabolism, Oxidative Stress<\/p>\n BIOINFORMATICS AND SYSTEMS BIOLOGY APPLIED TO BIOCHEMISTRY<\/strong><\/p>\n Use of bioinformatics and systems biology tools for problem solving in biochemistry. Creation of new software for evaluation of boanks of gene expression and proteomics.<\/p>\n Concentration Areas:<\/strong> Cellular Biology<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Lisiane de Oliveira Porci\u00fancula” module_id=”L” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/default-avatar.jpg” align=”center” _builder_version=”4.4.8″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.9.3″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false” hover_enabled=”0″ sticky_enabled=”0″]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 2 | Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n STUDIES ON THE PURINERGETIC SYSTEM<\/strong><\/p>\n Our research aims to understand the role of adenosine and its receptors in diseases that affect the brain during and after its development. Our group investigates the impact of caffeine administration (a non-selective antagonist of adenosine receptors) on the normal development of the brain and experimental models of neurodevelopmental diseases, evaluating behavioral, metabolic and electrophysiological changes.<\/p>\n Concentration Areas:<\/strong> Neurochemestry, Neuropharmacology, and Behaviour<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Luis Valmor Cruz Portela” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/default-avatar.jpg” align=”center” _builder_version=”4.4.8″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 2 | Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n NEURODEGENERATION MECHANISMS AND BIOMARKERS IN NEUROTRAUMA<\/strong><\/p>\n Cranio-Encephalic Trauma (TBI) can lead to premature death, cognitive and neuropsychiatric disorders, and even activate neurodegeneration mechanisms. Our laboratory tries to unravel the molecular and cellular mechanisms involved in these changes using experimental models and studies in patients. In addition, we are interested in developing innovative neuroprotection strategies.<\/p>\n Concentration Areas: <\/strong> Neurochemestry, Neuropharmacology, and Behaviour<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”M\u00e1rcia Kauer Sant\u2019Anna” module_id=”M” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/default-avatar.jpg” title_text=”Comiss\u00e3o de P\u00f3s-Gradua\u00e7\u00e3o” align=”center” _builder_version=”4.9.3″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 1D Research Productivity Scholarship | Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n FISIOPATHOLOGY OF MOOD DISORDERS<\/strong><\/p>\n The pathophysiology of mood disorders has not yet been fully elucidated, however, major advances in its clarification are being reported. Among the several studies carried out in recent years, the most significant findings are concentrated primarily in biological pathways related to neurotrophins, inflammation and oxidative stress, which are linked to neuroplasticity. In order to investigate the biochemical and molecular mechanisms involved in the pathophysiology of psychiatric disorders, the research group has used patient biological samples and experimental models (cell culture and animal models) together with techniques such as immunoassays, flow cytometry and confocal microscopy.<\/p>\n Concentration Areas:<\/strong> Neurochemestry, Neuropharmacology, and Behaviour<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Marcos Roberto de Oliveira” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/marcos_oliveira.jpg” title_text=”marcos_oliveira” align=”center” _builder_version=”4.9.0″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 2 | Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n Mitochondrial therapy based on natural molecules Mitochondria are the main organelles responsible for the synthesis of adenosine triphosphate (ATP) in human cells. They are also involved in calcium metabolism and the control of cellular fate, as they are central to the process called apoptosis. Different metabolic pathways occur wholly or partially in these organelles. Therefore, mitochondrial dysfunctions are the cause of cell death in several diseases. In this context, we investigated, in this line of research, natural molecules, mainly of plant origin, as agents to promote mitochondrial protection in experimental models in vitro, ex vivo, and in vivo.\n<\/p>\n Concentration Areas: [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Maria Elisa Calcagnotto” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/default-avatar.jpg” align=”center” _builder_version=”4.4.8″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Master’s Advisor | Doctoral Advisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n BASIC MECHANISMS OF EPILEPSY><\/p>\n Our research focuses on the intrinsic, synaptic and molecular mechanisms that regulate neuronal excitability and the involvement of the GABAergic system in epileptogenesis. Studying animal models of epilepsy and tissue obtained from patients undergoing surgery for difficult-to-control epilepsy, we hope to gain a better understanding of the cellular events underlying epileptic activity. The techniques used include in vivo electrophysiological records of brain and in vitro oscillations of cell membrane properties and synaptic function in tissue slices and cell culture; Morphological studies of neural network structure and expression of proteins by immunohistochemistry; And pharmacological analyzes.<\/p>\n Concentration Areas:<\/strong> Neurochemestry, Neuropharmacology, and Behaviour<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Maria Luiza Saraiva Pereira” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/default-avatar.jpg” align=”center” _builder_version=”4.4.8″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 2 | Master’s Advisor | Doctoral Advisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n CELLULAR AND MOLECULAR BIOLOGY OF HEREDITARY DISEASES<\/strong><\/p>\n To evaluate variations in genes sequences associated with hereditary disorders and the effect of these changes in the treatment of these patients, when treatment is available. The identification of new targets for the development of therapies is another focus of the line of research. To identify and evaluate the effect of nucleotide replications in patients with neurodegenerative diseases.<\/p>\n Concentration Areas:<\/strong> Cellular Biology<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Marina Concli Leite” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/marina_leite.jpg” title_text=”marina_leite” align=”center” _builder_version=”4.9.0″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Master’s Advisor | Doctoral Advisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n DIET, ADIPOCINES AND NEUROPROTECTION<\/strong><\/p>\n The type of diet affects metabolism, including that of the CNS. Thus diets \u201cdiabetes-genics\u201d, by effect of glucose or its derivatives (methylglyoxal or AGE) can cause damage to the CNS. On the other hand, caloric restriction and ketogenic diet have been proposed as protectors in certain neuropsychiatric diseases. Here we investigate endocrine mediators (eg, insulin, adipokines) and possible molecular targets and mechanisms of damage or protection to the CNS and peripheral (hepatic, renal and adipose) tissues in In vivo models and cell cultures.<\/p>\n Concentration Areas: <\/strong> Nutrition, Metabolism, Oxidative Stress<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Moacir Wajner” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/moacir_wajner.jpg” title_text=”moacir_wajner” align=”center” _builder_version=”4.9.2″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Research Productivity Scholarship 1A | Master’s Advisor | Doctoral Supervisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n STUDIES OF THE TOXICITY MECHANISMS OF THE ACCUMULATED METABOLITICS IN ORGANIC ACIDEMICS AND DEFECTS ON OXIDATION OF FATTY ACIDS<\/strong><\/p>\n To study the tissue toxicity mechanisms (brain, heart, liver and skeletal muscle) of carboxylic acids and their accumulated derivatives in organic acidemia, fatty acid oxidation defects and aminoacidopathies on redox homeostasis and mitochondrial energetics, as well as on the glutamatergic system (Brain) aiming to clarify the pathophysiology of these diseases and make possible new therapeutic strategies for them.<\/p>\n Concentration Areas:<\/strong> Innate Errors of the Metabolism<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,3_4″ use_custom_gutter=”on” admin_label=”Rachel Krolow Santos Silva Bast” module_id=”R” _builder_version=”4.4.8″ background_color=”#ffffff” custom_margin=”60px|||” custom_padding=”0px||0px|” animation_style=”fade” border_radii=”on|20px|20px|20px|20px” box_shadow_style=”preset1″ box_shadow_vertical=”50px” box_shadow_blur=”80px” box_shadow_color=”rgba(15,19,25,0.1)”][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/default-avatar.jpg” align=”center” _builder_version=”4.4.8″ width=”100%” width_tablet=”50%” width_phone=”50%” width_last_edited=”on|phone” module_alignment=”center” min_height_tablet=”” min_height_phone=”” min_height_last_edited=”on|phone” custom_margin=”||||false|false” custom_margin_tablet=”30px||||false|false” custom_margin_phone=”30px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||||false|false” animation_style=”fold” border_radii_tablet=”” border_radii_phone=”on|5px|5px|5px|5px” border_radii_last_edited=”on|phone” always_center_on_mobile=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_text _builder_version=”4.4.8″ text_text_color=”#333333″ text_line_height=”1em” link_text_align=”center” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” module_alignment=”center” custom_margin=”0px||||false|false” custom_padding=”||10px||false|false”]<\/p>\n \n [\/et_pb_text][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”4.4.8″ background_color=”#ffffff” custom_padding=”60px||60px|5%” custom_padding_tablet=”0px|40px|40px|40px|false|false” custom_padding_phone=”0px||||false|false” custom_padding_last_edited=”on|tablet” padding_tablet=”40px|40px|40px|40px” padding_last_edited=”on|tablet” custom_padding__hover=”|||”][et_pb_text _builder_version=”4.4.8″ text_font=”Nunito||||||||” text_font_size=”18px” text_line_height=”1.8em” header_font=”Montserrat|700||on|||||dotted” header_text_color=”#353740″ header_font_size=”40px” header_2_font=”Montserrat|700|||||||” header_2_font_size=”30px” header_4_font=”Montserrat|700|||||||” header_4_text_color=”#333333″ header_4_font_size=”26px” custom_margin_tablet=”” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|phone” animation_style=”fade”]<\/p>\n [\/et_pb_text][et_pb_accordion open_toggle_background_color=”#ffffff” closed_toggle_background_color=”#ffffff” _builder_version=”4.9.0″ toggle_text_color=”#2a2a2a” toggle_font=”Montserrat|600|||||||” toggle_font_size=”18px” toggle_line_height=”1.6em” closed_toggle_font=”Montserrat|600|||||||” body_font=”||||||||” body_line_height=”2em” max_width=”98%” max_width_tablet=”” max_width_phone=”” max_width_last_edited=”on|phone” custom_margin=”|||-10px” custom_margin_tablet=”|||-1px” custom_margin_phone=”” custom_margin_last_edited=”on|desktop” animation_style=”slide” animation_direction=”right” animation_intensity_slide=”5%” animation_starting_opacity=”100%” toggle_font_size_tablet=”” toggle_font_size_phone=”14px” toggle_font_size_last_edited=”on|desktop” border_width_all=”0px” border_color_all=”#ffa53b” border_width_left=”10px” border_color_left=”#009ece” box_shadow_style=”preset2″ box_shadow_horizontal=”0px” box_shadow_vertical=”35px” box_shadow_blur=”115px” box_shadow_spread=”-25px” box_shadow_color=”rgba(0,0,0,0.15)”][et_pb_accordion_item title=”Curriculum” open=”on” _builder_version=”4.9.0″ toggle_font=”Montserrat|600|||||||”]<\/p>\n \u2022 Master’s Advisor | Doctoral Advisor [\/et_pb_accordion_item][et_pb_accordion_item title=”Research Line” _builder_version=”4.9.0″ open=”off”]<\/p>\n NEUROBIOLOGICAL PROGRAMMING OF FOOD BEHAVIOR The consumption of different types of food during pregnancy or in early periods of life can program the metabolism and behavior of the adult animal. Early exposure to diets high in fat and \/ or sugar has demonstrated changes in the biochemical pathways that control homeostatic and hedonic eating behavior. Changes in hormones: leptin, adiponectin, ghrelin and insulin, have been observed in studies with animal models and also in humans, being one of the study objectives of the group. The study of biochemical markers related to neurogenesis and plasticity in different brain structures is also the focus of the study. With regard to behavior, the group studies possible changes caused by the early exposure of different types of food on food preference, memory, depression and anxiety in adulthood. In addition, the study of foods with a protective potential for behavior and for peripheral and central metabolism has also been studied in the laboratory.\n<\/p>\n Concentration Areas:<\/strong> Nutrition, Metabolism and Oxidative Stress<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" A C D E F G J L M R \u00a0 \u00a0\u00a0 \u00a0 Dra. Ana Maria Oliveira Battastini\u2022 Research Productivity Scholarship 1B | Master’s Advisor | Doctoral Supervisor \u2022 PhD in Sciences (Biochemistry) by Universidade Federal do Paran\u00e1, Brazil (1996) \u2022 Full Professor at Universidade Federal do Rio Grande do Sul, BrazilSTUDY OF PURINERGIC SIGNALING […]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":""},"yoast_head":"\n![\"Telefone](\"https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/icon-phone-blue.png\"){kind=icon}
<\/a>\u00a0 \u00a0![\"E-mail](\"https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/icon-email-blue.png\"){kind=icon}
<\/a>\u00a0 \u00a0![\"Lattes](\"https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/icon-lattes-blue.png\"){kind=icon}
<\/a>\n<\/p>\nDra. Ana Maria Oliveira Battastini<\/h4>\n
\u2022 PhD in Sciences (Biochemistry) by Universidade Federal do Paran\u00e1, Brazil (1996)
\u2022 Full Professor at Universidade Federal do Rio Grande do Sul, Brazil<\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDr. Andr\u00e9 Quincozes dos Santos<\/h4>\n
\n\u2022 PhD in Biological Sciences (Biochemistry) from the Universidade Federal do Rio Grande do Sul, Brazil (2010)
\n\u2022 Post-doctorate from the Universidade Federal do Rio Grande do Sul, Brazil (2014)
\n\u2022 Adjunct Professor I at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDra. Angela Terezinha de Souza Wyse<\/h4>\n
\n\u2022 PhD in Sciences (Biochemistry) from the Universidade Federal do Paran\u00e1, Brazil (1995)
\n\u2022 Full Professor at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDra. Carla Dalmaz<\/h4>\n
\n\u2022 PhD in Sciences (Biochemistry) from the Universidade Federal do Paran\u00e1, Brazil (1989)
\n\u2022 Post-doctorate from the University of California, United States (1992)
\n\u2022 Full Professor at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDr. Carlos Alberto Saraiva Gon\u00e7alves<\/h4>\n
\n\u2022 PhD in Sciences (Biochemistry) from the Universidade Fedeal do Paran\u00e1, Brazil (1992)
\n\u2022 Post-doctorate from the University of Newcastle, Australia (1995)
\n\u2022 Full Professor at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDr. Carlos Alexandre Netto<\/h4>\n
\n\u2022 PhD in Sciences (Biochemistry) from the Universidade Federal do Paran\u00e1, Brazil (1987)
\n\u2022 Post-doctorate from the University of London, England (1991)
\n\u2022 Full Professor I at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a><\/p>\nDra. Carmem Juracy Silveira Gottfried<\/h4>\n
\n\u2022 PhD in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Brazil (2000)
\n\u2022 Adjunct Professor IV at theUniversidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDra. Carmen Regla Vargas<\/h4>\n
\n\u2022 PhD in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Brazil (2000)
\n\u2022 Post-doctorate from the Universidade Federal de Santa Maria, Brazil (2002)
\n\u2022 Adjunct Professor IV at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDr. Clarissa Severino Gama<\/h4>\n
\n\u2022 Doctorate in Medicine: Medical Sciences at the Universidade Federal do Rio Grande do Sul Brazil (2004)
\n\u2022 Adjunct Professor III at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDr. Clovis Milton Duval Wannmacher<\/h4>\n
\n\u2022 PhD in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Brazil (1995)
\n\u2022 Full Professor at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDra. Cristiane Matt\u00e9<\/h4>\n
\n\u2022 PhD in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Brazil (2009)
\n\u2022 Adjunct Professor I at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDr. Daniel Pens Gelain<\/h4>\n
\n\u2022 PhD in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Brazil (2008)
\n\u2022 Post-doctorate from the Universidade Federal do Rio Grande do Sul, Brazil (2010)
\n\u2022 Adjunct Professor I at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDr. Diogo L\u00f6sch de Oliveira<\/h4>\n
\n\u2022 PhD in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Brazil (2008)
\n\u2022 Post-doctorate from the Universidade Federal do Rio Grande do Sul, Brazil (2010)
\n\u2022 Adjunct Professor I at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDr. Diogo Onofre Gomes de Souza<\/h4>\n
\n\u2022 PhD in Biochemistry from the Universidade Federal do Rio Janeiro, Brazil (1980)
\n\u2022 Post-doctorate from the University of London, England (1981)
\n\u2022 Full Professor at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0![\"Website](\"https:\/\/www.ufrgs.br\/ppgbioq\/wp-content\/uploads\/2021\/04\/icon-website-blue.png\"){kind=icon}
<\/a>\n<\/p>\nDr. Eduardo Rigon Zimmer<\/h4>\n
\n\u2022 PhD in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Brazil (2015)
\n\u2022 Post-doctorate from the Universidade Federal do Rio Grande do Sul, Brazil (2016)
\n\u2022 Adjunct Professor at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n
\n<\/strong> Neurochemistry, Neuropharmacology and Behavior<\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDr. F\u00e1bio Klamt<\/h4>\n
\n\u2022 PhD in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Brazil (2003)
\n\u2022 Post-Doctorate by the Center of Drug Evaluation and Research, Food and Drug Administration, United States (2006)
\n\u2022 Associate Professor I at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDr. Fabr\u00edcio Figueir\u00f3<\/h4>\n
\n\u2022 PhD in Biochemistry from the Universidade Federal do Rio Grande do Sul, Brazil (2015)
\n\u2022 Post-Doctorate in Biochemistry from the Universidade Federal do Rio Grande do Sul, Brazil (2017).
\n\u2022 Adjunct Professor at the Universidade Federal do Rio Grande do Sul, Brazil. <\/p>\n
\nI. Participation of the purinergic system in immune modulation, mainly by ATP, through binding to P2 receptors, and by adenosine, through binding to P1 receptors.
\nII. Participation of extracellular vesicles in immune modulation, mainly through the effects performed by exosomes.
\nIII. Evaluation of pharmacological interventions in preclinical cancer models, involving the immune system, the purinergic system and \/ or extracellular vesicles.<\/p>\n
\n<\/strong> Cellular Biology<\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDra. F\u00e1tima Theresinha Costa Rodrigues Guma<\/h4>\n
\n\u2022 PhD in Sciences (Biochemistry) from the Universidade Federal do Paran\u00e1, Brazil (1992)
\n\u2022 Full Professor at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDr. Guilhian Leipnitz<\/h4>\n
\n\u2022 PhD in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Brazil (2009)
\n\u2022 Post-doctorate from the Universidade Federal do Rio Grande do Sul, Brazil (2010)
\n\u2022 Adjunct Professor at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDra. Jade de Oliveira<\/h4>\n
\n\u2022 PhD in Biochemistry from the Universidade Federal do Santa Catarina, Brazil (2015)
\n\u2022 Post-Doctorate in Neuroscience from the Universidade Federal de Santa Catarina, Brazil (2016)
\n\u2022 Adjunct Professor at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n
\n<\/strong><\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDr. Jos\u00e9 Cl\u00e1udio Fonseca Moreira<\/h4>\n
\n\u2022 PhD in Sciences (Biochemistry) from the Universidade Federal do Paran\u00e1, Brazil (1995)
\n\u2022 Full Professor at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDra. Lisiane de Oliveira Porci\u00fancula<\/h4>\n
\n\u2022 PhD in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Brazil (2003)
\n\u2022 Post-Doctorate by the University of Coimbra, Portugal (2005)
\n\u2022 Adjunct Professor III at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDr. Luis Valmor Cruz Portela<\/h4>\n
\n\u2022 PhD in Biological Sciences (Biochemistry) from the Universidade Federal do Rio Grande do Sul, Brazil (2002)
\n\u2022 Adjunct Professor III at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDra. M\u00e1rcia Kauer Sant\u2019Anna<\/h4>\n
\n\u2022 PhD in Biological Sciences (Biochemistry) from the Universidade Federal do Rio Grande do Sul, Brazil (2007)
\n\u2022 Postdoctoral fellow at the University of British Columbia, Canada (2009)
\n\u2022 Adjunct Professor III at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDr. Marcos Roberto de Oliveira<\/h4>\n
\n\u2022 PhD in Biological Sciences (Biochemistry) from the Universidade Federal do Rio Grande do Sul, Brazil (2010)
\n\u2022 Adjunct Professor A-I at theUniversidade Federal do Rio Grande do Sul, Brazil <\/p>\n
\n<\/strong><\/p>\n
\n<\/strong> Metabolism and Bioenergetics and Neurochemistry\n<\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDra. Maria Elisa Calcagnotto<\/h4>\n
\n\u2022 PhD in Neurology \/ Neuroscience from the Universidade Federal de S\u00e3o Paulo, Brazil (2006)
\n\u2022 Post-Doctorate in Neurophysiology by the Montreal Neurological Insitute – McGill University, Canada (2000)
\n\u2022 Post-Doctorate in Neurophysiology from the University of California in San Francisco (UCSF), United States (2005)
\n\u2022 Post-Doctorate in Neurophysiology at the Universidade Federal de S\u00e3o Paulo, Brazil (2008)
\n\u2022 Post-Doctorate in Neurophysiology at the Andalusian Center for Molecular Biology and Regenerative Medicine (CABIMER), Spain (2010)
\n\u2022 Post-Doctorate in Neurochemistry – Neurophysiology at the Universidade Federal do Rio Grande do Sul, Brazil (2013)
\n\u2022 Adjunct Professor at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDra. Maria Luiza Saraiva Pereira<\/h4>\n
\n\u2022 PhD in Molecular Genetics from the University of London, England (1994)
\n\u2022 Post-doctorate from the University of Oxford, England (1995)
\n\u2022 Full Professor at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDra. Marina Concli Leite<\/h4>\n
\n\u2022 PhD in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Brazil (2010)
\n\u2022 Adjunct Professor I at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDr. Moacir Wajner<\/h4>\n
\n\u2022 PhD in Basic Sciences from the University of Newcastle Upon Tyne, England (1982)
\n\u2022 Post-doctorate from Universit\u00e4t Heidelberg (Ruprecht-Karls), Germany (1993)
\nMolecular, Enzymology and Chemistry of Macromolecules
\n\u2022 Full Professor at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n<\/a>\u00a0 \u00a0<\/a>\u00a0 \u00a0<\/a>\n<\/p>\nDra. Rachel Krolow Santos Silva Bast<\/h4>\n
\n\u2022 PhD in Biochemistry from the Universidade Federal do Rio Grande do Sul, Brazil (2013)
\n\u2022 Post-Doctorate in Biochemistry from the Universidade Federal do Rio Grande do Sul, Brazil (2015)
\n\u2022 Expertise in Biochemistry and Neuroscience
\n\u2022 Adjunct Professor at the Universidade Federal do Rio Grande do Sul, Brazil <\/p>\n
\n<\/strong><\/p>\n