Process for obtaining antifungal compounds – Vitrine Tecnológica (Technology Showcase)

Technology background

Inventors comes prospecting the broad spectrum antifungal activity in different classes of novel molecules in order to identify more active and less toxic alternative to the currently available classes in medical clinic.

Technology description

The present invention provides an efficient process for the preparation of new antifungal agents with potential application in the pharmaceutical field. The process for obtaining the compounds consists of the reaction between allyl bromides and potassium selenocyanate.

Problem Fixed

Controlling the spread of multi-resistant microorganisms.

Advantages

– Compounds are prepared from commercially available reactants;

– Activity of the compounds synthesized (allylic selenocyanates) it is the same or less than the drugs normally used for treatment of diseases caused by fungi tested.

Applications

– Antimicrobial and antiseptic agents;

– Industry pharmaceutical chemistry.

Nível de Maturidade da Tecnologia (TRL – Technology Readiness Level)