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| gp140 | IL-3, IL-5, GM-CSF | Jak2 | Stat5 |
| gp130 | IL-6,
IL-11, OSM, CNTF
G-CSF, LIF, CNTF, CT-1 IL-12 Leptin |
Jak1,
-2, Tyk2
Jak2, Tyk2 Jak2 |
Stat1,-3,-5
Stat4 Stat3,-5 |
| IL-2 | IL-2,
IL-7, IL-9, IL-15
IL-4 IL-13 |
Jak1,
-3
Jak1, -3 Jak1, -2, Tyk2 |
Stat5,
-3, -1
Stat6 Stat6 |
| Growth Hormone | GH
TPO PRO, EPO |
Jak2
Jak2 Jak2 |
Stat5,
-3, -1
Stat3,-5 Stat5 |
| Interferons | IFNa,
IFNb
IFNg IL-10 |
Jak1,
Tyk2
Jak1,-2 Jak1, Tyk2 |
Stat1,
-2, -3, -5
Stat1 Stat3,-1 |
| RTKs | EGF/ErbB,
TGFa, PDGF
CSF-1
Insulin bFGF HGF |
Stat1,
-3, -5
Stat5,-3 Stat1,-3 Stat3 |
|
| GPCRs | Angiotensin
Serotonin a-Thrombin CXCR4 |
Jak2,
Tyk2
Jak2 Jak2,-3 |
Stat1,-2,-3
Stat3 Stat3 |
Copyright © 2001-2014 Daniele Focosi.
All rights reserved
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