ESICANCER

Evolutionary in silico Cancer Simulator

esiCancer is a computational tool designed to simulate cancer evolution using the genetic information of real cancers to reconstruct the evolutionary history of cancer.

For description and detailed instructions on how to use this tool, read the esiCancer manuscript and watch the informative videos. Please follow the link to the original article.

Tumour evolution as modeled by esiCancer

Resources

Download esiCancer 1.1 software for , or .

For information about updates, see the history of esiCancer versions.

For macOS High Sierra or less, please follow the instructions to install.
Download esiCancer documentation.
Use these spreadsheets as examples for esiTable and interaction Table to perform your simulation.
Use these files as an example of analysis of esiCancer output. Included you will find a guide and spreadsheets to construct some of the figures presented in the esiCancer videos and article.
To construct your esiTable or interaction Table using real genomic data, you can use the following tools:
- This script can be used with TCGA data.
- The Select algorithm from Ciriello Lab can be used to analyze interactions (ME and CO) between alterations in cancer.
All the code for esiCancer and other information can be found at GitHub.
esiCancer is under GNU Public License v3.0. If you make any improvement in the code, please let us know so we can maintain all versions of esiCancer freely available to the public.