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SERVICES Cell Biology

The establishment of the Cellular Biology area at CBiot, focusing on the study of cell structure and function, has allowed us to advance our understanding of human and animal pathogens, as well as tumor and plant development. This expertise has supported direct contributions to society, such as our involvement in expanding the Petrochemical Hub of Triunfo by conducting rigorous assessments of safety and genotoxicity. In addition to service provision in this area, research such as the discovery of a new mechanism for inhibiting biofilm formation opens up perspectives for developing new control mechanisms, reducing damage to various industrial structures such as cooling and fuel pipelines, vessel propellers, optical equipment, as well as buildings and artworks such as paintings and statues.

This know-how was essential in the commercial production of Taq DNA polymerase in Brazil in the 1990s by CBiot, offering antibody production services, developing vaccines for bovine ticks, or researching the process of cell death in tumor cells, with direct implications for the development of new drugs. Lastly, to support these initiatives, CBiot established the MULTI BIOCEL LAB - CBiot Cellular Biology Multi-User Laboratory, equipped with 2 Incucytes, also serving as support for companies incubated at IECBiot.

Publications

One of the indicators of the impact of CBiot's activities on Gaúcho and Brazilian societies is the quantity and quality of articles published by our researchers in highly relevant international journals, often subject to interactions with the productive sector.

Most of these works are associated with the training activities of our students into new high-level researchers, ready to tackle societal problems, whether in teaching, research institutes, or technology-based companies.

  • A longitudinal transcriptomic analysis of Rhipicephalus microplus midgut upon feeding| 2024 | TICKS AND TICK-BORNE DISEASESLu, Stephen and Waldman, Jessica and Parizi, Luis Fernando and Vaz Junior, Itabajara da Silva and Tirloni, Lucas
  • Xanthan-carrageenan film containing sesame seed oil: A nanocomposite pharmaceutical platform for trichomoniasis treatment| 2024 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULESSaccol, Camila Parcianello and Cervi, Veronica Ferrari and Blume, Julia Carine and Menezes, Agata Giuseppe and Apel, Miriam Anders and da Rosa, Lucas Saldanha and Tasca, Tiana and Cruz, Leticia
  • The use of gene expression datasets in feature selection research: 20 years of inherent bias?| 2024 | WILEY INTERDISCIPLINARY REVIEWS-DATA MINING AND KNOWLEDGE DISCOVERYGrisci, Bruno I. and Feltes, Bruno Cesar and Poloni, Joice de Faria and Narloch, Pedro H. and Dorn, Marcio
  • Theoretical models of staurosporine and analogs uncover detailed structural information in biological solution| 2024 | JOURNAL OF MOLECULAR GRAPHICS \& MODELLINGFontana, Crisciele and de Meirelles, Joao Luiz and Verli, Hugo
  • Detection of Trichomonas vaginalis by Allplex™ STI Essential Assay (Seegene) in clinical samples from the Brazilian public health system users| 2024 | EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY \& INFECTIOUS DISEASESFreitas, Mariana Dicki and Cardoso, Fernanda Gomes and Rigo, Graziela Vargas and Machado, Hanalydia de Melo and Bazzo, Maria Luiza and Tasca, Tiana

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