CELL ANABOLISM AND CATABOLISM (METABOLOMICS)
(for structural features of involved molecules see the General biochemistry section) General resources for metabolic pathways (more tools are listed under Protein tools)
  • Boehringer-Mannheim "Biochemical Pathways" maps at ExPASy : keyword search
  • Medical Biochemistry by M.W.King at Terre Haute Center for Medical Education (THCME), University of Indiana
  • Human metabolic pathways of biochemistry (includes DG° values)
  • Kyoto Encyclopedia of Genes and Genomes (KEGG) : metabolic and regulatory pathways
  • Main Metabolic Pathways (MMP) on Internet
  • Metabolic Pathways - Minimaps
  • Protein Function and Biochemical Pathways (PFBP) Project
  • WIT/MPW metabolic pathways by Evgeni Selkov
  • Enzymes and Metabolic Pathways (EMP) database (updated with over 8,000 records a year to cope with the essentials published in the literature each year)
  • LIGAND (Ligand chemical database for enzyme reactions)
  • Biomolecular relations in information transmission and expression (BRITE) in the KEGG metabolic pathways
  • BRENDA (from enzyme to substrate(s) & product(s))
  • Biocatalysis/Biodegradation Database at University of Minnesota
  • The ENZYME data bank at ExPASy (EC number, Recommended name, Alternative names, Catalytic activity, Cofactors, Pointers to the SWISS-PROT entrie(s) and disease(s) associated with a deficiency)
  • BioCarta
  • Pathways+ (under construction)
  • Biological Biochemical Image Database (BBID) (pathway images, structures and gene families)
  • Biomolecular Interaction Network Database (BIND)
  • Interactive Metabolic Pathways Reports
  • Klotho (Biochemical Compounds Declarative Database)
  • Biochemical Pathway Database and Analysis System (BPDAS)
  • Transpath : gene-regulatory pathways involved in the regulation of transcription factors in man, mouse and rat
  • Composite regulatory elements in eukaryotes (COMPEL) at Gene REgulatory Sequence Analysis (GRESA)
  • Database of Interacting Proteins (DIP)
  • Functional networks (FunkNet) at EML
  • The metabolic database of soybean genetic database (SoyBase)
  • Usenet bionet.metabolic-reg
  • Specific resources
    lipoproteins
    Mr (MDa)
    density (g/dL)
    Ø (nm)
    triglycerids
    cholesterol phospholipids
    apolipoproteins
    chylomicrons
    400
    0.95
    1200-75
    80-95% (from diet)
    2-7%
    3-9%
    A-I, A-II, A-IV, A-V, B-48, C-I, C-II, C-III, E, M
    chylomicron remnants : partially metabolized chylomicrons that have lost most of their triglycerides via degradation in muscle and adipose tissue but retain their cholesteryl esters; they reenter the bloodstream and are taken up into hepatic cells via receptor-mediated endocytosis. Within the liver, they are digested and their cholesteryl esters cleaved to generate free cholesterol. 
    << 1.506
    500-80
    diet triglycerids


    A-I, A-II, A-IV, A-V, B-48, C-I, C-II, C-III, E, M
    very large density lipoproteins (VLDL) / pre-b-lipoproteins
    10-80
    0.95-1.006
    80-30 (directly relates to amount of available triglycerids => convertibility to LDL)
    55-80% (endogenous)
    5-15%
    10-20%
    B-100, C-I, C-II, C-III, E
    intermediate density lipoproteins (IDL)
    5-10
    1.006-1.019
    35-25
    20-50%
    20-40%
    15-25%
    B-100, C-I, C-II, C-III, E
    low density lipoproteins (LDL) / b-lipoproteins large LDL
    2.3
    1.019-1.063
    25-18
    5-15%
    40-50%
    20-25%
    B-100, M
    small dense LDL (susceptible to oxidation, binds proteoglycan, permeates arterial wall)






    high density lipoproteins (HDL) / a-lipoproteins HDL1
    0.17-0.36
    1.063-1.210
    12-5
    5-10%
    15-25%
    20-30%
    A-I (70-80%; very protective role), A-II, C-I, C-II, C-III, D, E, F, J, L1, M, SAA
    HDL2 (larger, more cholesterol)






    HDL3 (smaller, less cholesterol)






    lipoproteins (a) (Lp(a))
    1.055-1.085
    30
    cholesterol esters


    B-100, M, (a)
    Bibliography
    Copyright © 2001-2014 Daniele Focosi. All rights reserved Terms of use  | Legal notices
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    Copyright © 2001-2014 Daniele Focosi. All rights reserved Terms of use  | Legal notices
    About this site  |  Site map  |  Acknowledgements | Open forum  |    |  Current link partners
     Abbreviations and acronyms  |  Medical terminology  |  Add a link  |  Translate   |  Softwares


    This website subscribes to the
          HONcode principles of the HON Foundation. Click to verify.
    PicoSearch
     

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